How Much is Amoxicillin Without Insurance in 2025?
In a hurry? A 10-day course of generic amoxicillin 500 mg costs as little as $2.94 with a coupon and rarely more than $40 cash in 2025. Walmart and Cost Plus Drugs sit at the low end (under $10), while CVS or Walgreens usually land in the $15 – $35 range. Free-antibiotic programs (Publix) and sliding-fee clinics can drop that to $0 if you qualify. Finish the full prescription and follow CDC stewardship advice to curb resistance.
Cash-Price Snapshot (10-day / 21-capsule 500 mg course)
| Pharmacy / Source | Advertised Low Price* | Typical Range |
|---|---|---|
| Walmart – $4 Generics list | $4 (30-day supply) Walmart.com | $4 – $15 |
| GoodRx coupon (multiple chains) | $2.94 at select stores GoodRxGoodRx | $3 – $12 |
| Cost Plus Drugs (mail order) | $6.79 for 30 caps Homepage of Mark Cuban Cost Plus Drugs | $7 – $10 incl. shipping |
| CVS | $15 – $30 walk-in (2025 price checks) Publix Super Markets | $15 – $30 |
| Walgreens | $15 – $35 cash GoodRx | $15 -$35 |
| Rite Aid / Kroger | $15 – $30 (store-card discounts may drop below $20) | $15 – $30 |
| Publix | Free 14-day supply if drug is in the “free antibiotics” list Publix Super Markets Publix Super Markets | $0 |
*Prices reflect April 2025 cash quotes or posted coupon values; always confirm locally.
Key point up-front: Amoxicillin’s cash price swings because who sells it, where you buy it, and what strength you need all change the pharmacy’s wholesale cost, mark-up, or both. But once you know the three main cost drivers—and the quick fixes under each—you can almost always force the bill back down into the $4-$15 zone.
Why Amoxicillin Prices Jump & How You Can React
| Cost Driver | What It Means in 2025 | Typical Price Impact | Action You Can Take |
|---|---|---|---|
| Pharmacy mark-ups & buying power | Big boxes (Walmart, Target-CVS) negotiate rock-bottom wholesaler rates and advertise amoxicillin on $4 generic lists, while small independents set their own margins. Walmart.com GoodRx | $2–$25 difference for the same 21-count, 500 mg script. | Price‐check any independent against Walmart’s $4 price or a GoodRx coupon; most will match or you can transfer the script. |
| Geography & local competition | Studies show pharmacies in low-competition or rural ZIP codes charge 9 % more for common generics. PMC | About $2–$5 higher than urban chains. | Use online coupon tools to locate the cheapest chain within driving distance, or switch to mail-order (Cost Plus $6.79 delivered). Homepage of Mark Cuban Cost Plus Drugs Homepage of Mark Cuban Cost Plus Drugs |
| Dosage & formulation | Higher strengths (875 mg) or pediatric suspensions move off the $4 lists and add $3–$10. Augmentin (adds clavulanate) starts around $20 even with coupons. GoodRx GoodRx | $3–$10 bump for high-dose amox; $10–$30 bump for Augmentin. | Ask the prescriber if splitting lower-dose tablets is clinically OK; compare coupon prices for both forms—sometimes 2×500 mg tabs are cheaper than 1×875 mg. |
Quick Fixes Mapped to Each Driver
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Always run a coupon search (GoodRx, SingleCare) before you pay—lowest 2025 price is $2.94. GoodRx
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Leverage big-box generics lists: Walmart still fills 30 amoxicillin 500 mg caps for $4. Walmart.com
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Mail-order when local quotes are high: Cost Plus ships 30 caps for $6.79; Amazon and Blink average $6–$12. Homepage of Mark Cuban Cost Plus Drugs Homepage of Mark Cuban Cost Plus Drugs
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Use loyalty clubs (Kroger Rx Savings, Rite Aid Rewards) to shave another $3–$5. ScienceDirect
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Check “free” programs first—Publix still dispenses a 14-day amoxicillin supply at $0 in participating states. Publix Super Markets
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If you’re remote or uninsured, HRSA sliding-fee clinics can waive or cap drug costs based on income. PMC
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Ask the pharmacist to compare coupon/cash vs. insured copay—post-2025 PBM reforms often make cash cheaper than plans. WSJ
How To Save
| # | Strategy | Typical Savings | How to Do It / Notes |
|---|---|---|---|
| 1 | Use a coupon aggregator (GoodRx, SingleCare) | Up to 80 % off retail—prices as low as $2.94 for 500 mg/21 caps | Search the drug + ZIP code, print or show the coupon at checkout GoodRx |
| 2 | Pick a low-price chain (Walmart, Target-CVS) | $4–$15 cash for a standard course | Walmart’s generic-value list advertises many antibiotics under $10; always confirm your store’s current list Walmart.com |
| 3 | Order by mail from Cost Plus Drugs | About $6.79 for 30×500 mg tablets, plus $5 shipping | Create a free account, upload script, get two-day shipping nationwide Homepage of Mark Cuban Cost Plus DrugsHomepage of Mark Cuban Cost Plus Drugs |
| 4 | Ask about store savings clubs (Kroger, Rite Aid) | Shaves $3–$5 off many generics | Kroger Rx Savings Club and similar loyalty programs drop member pricing below posted cash rates Kroger |
| 5 | Use HRSA sliding-fee clinics | Fees reduced up to 100 % based on income | Federally Qualified Health Centers apply a sliding-fee scale for visits and prescription fills Bureau of Primary Health Care |
| 6 | Check live “menu” prices online | Finds sub-$10 options in minutes | New CMS transparency rules push pharmacies to post real-time cash prices, making comparison-shopping easier Pharmacy Times |
| 7 | Leverage PBM-reform savings | Cash price sometimes beats your plan copay | Ask the pharmacist to compare the coupon/cash quote with your insurance price; spread-pricing crackdowns can widen that gap Pharmacy Times |
| 8 | Use alternate mail-order sites (Amazon Pharmacy, Mark Cuban Cost Plus) | $6–$12 delivered for most strengths | Ideal if local chains quote $20+; many telehealth platforms auto-route to these low-cost pharmacies Homepage of Mark Cuban Cost Plus Drugs |
| 9 | Look for truly free fills (Publix, select clinics) | $0 for a 14-day supply | Publix’s long-running program still covers amoxicillin in participating states; show any valid prescription Publix Super Markets |
Financial Assistance Programs
For those worried about the cost of Amoxicillin without insurance, several avenues can help:
- Manufacturer Coupons: Check the manufacturer’s website for potential coupons.
- Non-Profit Aid: Certain organizations assist low-income individuals with medication costs.
- Pharmacy Savings Cards: Cards like GoodRx or SingleCare can provide significant discounts at the register.
Additionally, the Health Resources & Services Administration (HRSA) supports federally qualified health centers, which may offer medications at reduced costs.
1. Price-Transparency Rules Tighten
Online “menu pricing” is becoming mandatory
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Hospitals and many pharmacies must now post their standard charges online under CMS price-transparency regulations updated for 2025, making it far easier to comparison-shop from a phone. CMS
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Health-plan transparency files, live since 2022, are spawning consumer apps that scrape real-time cash prices for common generics, including antibiotics. CMS
Coupon engines amplify competition
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GoodRx still lists “as low as $2.94” cash coupons for amoxicillin 500 mg at select chains in 2025. U.S. Food and Drug Administration
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Mark Cuban’s Cost Plus Drugs undercuts many walk-in stores at $6.79 for 30 tablets delivered. Homepage of Mark Cuban Cost Plus Drugs WIRED
FAQs
How much is Amoxicillin out of pocket?
Paying out of pocket for Amoxicillin can range from $10 to $40 for a standard course. Prices vary by pharmacy and location, and discounts or coupons can reduce costs significantly.
How much is Amoxicillin without insurance at CVS?
At CVS, a typical 10-day course of Amoxicillin (500 mg) may cost between $15 and $30 without insurance. Liquid formulations or pediatric dosages may differ slightly in price.
How much is Amoxicillin at Walgreens?
Walgreens’ prices are generally comparable to CVS, ranging from $15 to $35 for a standard adult prescription. Always check for store promotions and discount cards.
How much is antibiotics if you don’t have insurance?
Without insurance, antibiotic prices can vary widely, from around $8 for common generic types to over $100 for newer or brand-name medications. It’s crucial to shop around and look for discounts.
How Much is Amoxicillin for Kids Without Insurance?
Parents often ask how much is Amoxicillin for kids without insurance. Children’s dosages can vary widely based on weight and the type of infection. On average, a pediatric prescription for liquid Amoxicillin could be $10 to $25. Some pharmacies and community health clinics offer discounted rates for children’s medications, so it’s worth asking about local programs.